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GHK-Cu is a research peptide–copper complex composed of the tripeptide Gly-His-Lys bound to copper (II) ions, widely studied for its role in cellular signaling and extracellular matrix modulation. Preclinical research suggests GHK-Cu may support collagen regulation, gene expression, and antioxidant enzyme activity through copper-mediated redox mechanisms, making it a key compound in tissue remodeling, metalloprotein regulation, and regenerative biochemistry research.